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58 As a result, folinic acid, and its synthetic counterpart, leucovorin, are employed in MTX rescue therapy because they can displace MTX from DHFR and restore intracellular folate stores with fully reduced folate

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Abbreviations AI: Artificial intelligence CNC: Cellulose nanocrystals DFU: Diabetic foot ulcer EPS: Extracellular polymeric substances GOx: Glucose oxidase LCA: Life cycle assessment MMPs: Matrix metalloproteinases NC: Nanocellulose PLA: Polylactic acid ROS: Reactive oxygen species SCFA: Short-chain fatty acids TMAO: Trimethylamine N-oxide ECM: Extracellular matrix CFU: Colony-forming units References Collaborators GBDCoD